Genomics

Genome Web by Applied Biosystems Extensive source of genome-related news http://genomeweb.com/ LigerCat Literature & Genomics Resource Catalogue search tool http://ligercat.ubio.org/ KEGG: Kyoto Encyclopedia of Genes and Genomes A bioinformatics resource named KEGG is part of the research projects of the Kanehisa Laboratories in the University of Tokyo to nable computational prediction of higher-level complexity of cellular processes and organism behaviors from genomic and molecular information. http://www.genome.ad.jp/kegg/ The Human Genome Sequencing Center (HGSC) The Human Genome Sequencing Center (HGSC) was established in 1996 when the National Human Genome Research Institute (NHGRI) designated Baylor College of Medicine as one of six pilot programs for the final phases of the Human Genome Project (HGP).  The HGP is now in a new phase of exploring individual DNA sequence variation and its association with human diseases. The HGSC is characterizing normal genetic variation in human populations. The results are anticipated to change the way we understand disease and other life processes. http://www.hgsc.bcm.tmc.edu/ CBS Genome Atlas Database Easy-to-use summary of genomic information currently available for all organisms from Center for Biological Sequence Analysis (CBS), The Technical University of Denmark. http://www.cbs.dtu.dk/services/GenomeAtlas-3.0/ Rat Genome Database "The Rat Genome Database (RGD) curates and integrates rat genetic and genomic data and provides access to this data to support research using the rat as a genetic model for the study of human disease". http://www.rgd.mcw.edu/ Human Genome Project Information by the Department of Energy Genome programs of the U. S. Department of Energy Office of Science is a founder of the Human Genome Project and leader in systems biology research http://www.ornl.gov/sci/techresources/Human_Genome/project/journals/journals.shtml HAPMAP The International HapMap Project is a partnership of scientists and funding agencies from Canada, China, Japan, Nigeria, the United Kingdom and the United States to develop a public resource that will help researchers find genes associated with human disease and response to pharmaceuticals. http://www.hapmap.org/ UniProt: protein sequence and function The mission of UniProt is to provide the scientific community with a comprehensive, high-quality and freely accessible resource of protein sequence and functional information. UniProt provides access to the UniProtKB Protein knowledgebase, which consists of two sections, including Swiss-Prot, which is manually annotated and reviewed, and TrEMBL, which is automatically annotated and is not reviewed. UniRef Sequence clusters is used to speed up similarity searches, and UniParc Sequence archive can be used to keep track of sequences and their identifiers. UniProt also provides access to supporting data, literature citations, taxonomy, keywords and more. http://www.uniprot.org/ Center for Structural Genomics of Infectious Diseases CSGID applies state-of-the-art high-throughput (HTP) structural biology technologies to experimentally characterize the three dimensional atomic structure of targeted proteins from pathogens in the NIAID Category A-C priority lists and organisms causing emerging and re-emerging infectious diseases. The three dimensional structure of proteins will assist drug design and development by yielding direct insights into the target molecular mechanisms, in interaction with other biological molecules, or with synthetic compounds, in order to improve selectivity, specificity and optimize drug development in a rational way. http://www.csgid.org/csgid/cake/